Compiled By Jessica Oesterheld,
M.D. and David Osser M.D.
Here are some useful links on drug interactions and metabolism. To appreciate the full benefits of this information, click here to get a free 30-day trial version of GeneMedRx. This metabolism-based drug interaction software predicts response to medication combinations with optional input of genetic variations.
Cytochromes (P450)
CYP
Allelic Nomenclature committee
David
Nelson’s homepage
General
Source for links to other CYP Web pages Kirill N. Degtyarenko's
Directory of P450-containing Systems
CYP
Table
UGTs
Nomenclature
www.pharmacogenomics.pha.ulaval.ca/sgc/ugt_alleles/
Review Article
www.psy.psychiatryonline.org/cgi/content/full/43/1/77
Transporters
Human
ATP-Binding Cassette Transporter Superfamily (ABC) including Pgps
(ABCB1)
Nomenclature
www.genenames.org/genefamily/abc.php
http://nutrigene.4t.com/humanabc.htm
Review article
PGPs
in AIDS - discussion and interactions table
Human
Solute-Linked Carrier Transporter Superfamily (SLC)
Nomenclature
www.tcdb.org/hgnc_explore2.php?stem=SLC
FDA
Medwatch
AIDs drug information and drug
interactions
www.hiv-druginteractions.org/
www.aidsinfo.nih.gov/DrugsNew/Default.aspx
How to get the product information
on a drug
Open list
of all drug company web sites,
then go to product list and hit prescribing information
Or go to google- type in trade name
and prescribing information
Qtc-prolonging drugs
List
PharmGKB
PharmGKB curates information
that establishes knowledge about the relationships among drugs,
diseases and genes, including their variations and gene products.
Our mission is to catalyze pharmacogenomics research.
Learning about DDIs: Outstanding Articles
A
review of DDIs with many tables
Grapefruit
drug interactions
Clinically
Significant DDIs
DDIs
in OPD
Review
of CYP-based DDIs
Overview
of Psychotropic Drug-Drug Interactions
Guide
to Psychiatric DDIs
DDIs-
how to avoid them
Detrimental
DDIs in Antidepressants
Clinical
Relevance of Drug–Drug and Herb–Drug Interactions Mediated
by the ABC Transporter ABCB1 (MDR1, P-glycoprotein)
UGT
drug interactions
Overview
of DDIs
GeneMedRx has not been reviewed or approved by the United States Food and Drug Administration and cannot be used to diagnose or treat any disease or other health condition.
